Nanopore-based single-molecule mass spectrometry on a lipid membrane microarray
Baaken G., Ankri N., Schuler A.K., Rühe J., Behrends C.
Am. Chem. Soc Nano, 5(10), 8080-8088, 2011
Download the full paper here |
User publication: 'Functional analysis of synthetic substructures of polytheonamide B: A transmembrane channel-forming peptide'
Matsuoka S, Shinohara N, Takahashi T, Iida M, and Inoue M
Angew. Chem. Int. Ed., 50, 4879 – 4883, 2011
Download the full paper here. |
User Publication: 'Green fluorescent protein changes the conductance of connexon 43 hemichannels reconstituted in planar lipid bilayers'
Christian Carnarius , Mohamed Kreir, Marcel Krick, Christoph Methfessel, Volker Moehrle, Oliver Valerius, Andrea Brüggemann, Claudia Steinem, Niels Fertig
Journal of Biological Chemistry, Published on December 3, 2011 as Manuscript M111.319871
Download the full paper here
|
State-of-the-art automated patchclamp devices: heatactivation, actionpotentials, and highthroughput in ionchannel screening
Sonja Stoelzle, Alison Obergrussberger, Andrea Brüggemann, Claudia Haarmann, Michael George, Ralf Kettenhofen and Niels Fertig
Frontiers in Pharmacology, November 2011, Volume 2 , Article 76
Download the full paper here
|
User Review: 'Automated electrophysiology makes the pace for cardiac ion channel safety screening'
Clemens Möller, Harry Witchel
Frontiers in Pharmacology, November 2011, Volume 2, Article 73
Download the full paper here |
User Publication: 'Thermo-sensitive transient receptor potential vanilloid channel-1 regulates intracellular calcium and triggers chromogranin A secretion in pancreatic neuroendocrine BON-1 tumor cells'
Stefan Mergler, Marek Skrzypski, Maciej Sassek, Piotr Pietrzak, Christina Pucci, Bertram Wiedenmann, Mathias Z. Strowski
Cellular Signalling 24 (2012) 233–246
Download the full paper here |
User Publication: 'Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells'
Stefan Mergler,, Monika Valtink, Katrin Taetz, Monika Sahlmüller, Gabriele Fels, Peter S. Reinach, Katrin Engelmann and Uwe Pleyer
Experimental Eye Research 93 (2011) 710e719
Download the full paper here |
Chimeric approach reveals that differences in the TRPV1 pore domain determine species-specific sensitivity to block of heat activation
Papakosta M., Dalle C., Haythornthwaite A., Cao L., Stevens E.B., Burgess G., Russell R., Cox P.J., Phillips S.C., Grimm C.
J. Biol. Chem., 2011 Sep 12. [Epub ahead of print]
Download the full paper here |
User Publication: 'Thermosensitive transient receptor potential channels in human corneal epithelial cells'
Mergler S., Garreis F., Sahlmüller M., Reinach P.S., Paulsen F., and Pleyer U.
J. Cell. Physiol., 2011, 226, 1828 - 1842
Download the full paper here  (1.29 MB) |
User Publication: 'Physiologie des humanen Hornhautendothels - neue Erkenntnisse durch elektrophysiologische Untersuchungen'
Mergler S. and Pleyer U.
Klin. Monatsbl. Augenheilkd., 2011, 228, 520 - 524
Download the full paper here (230 kB) |
User Publication: 'Rapid and Contrasting Effects of Rosiglitazone on Transient Receptor Potential TRPM3 and TRPC5 Channels'
Majeed Y, Bahnasi Y, Seymour VAL, Wilson LA, Milligan CJ, Agarwal AK, Sukumar P, Naylor J, and
Beech DJ
Mol. Pharmacol., 79(6),1023-30, 2011
Download the full paper here. |
Automated Patch Clamp on mESC-Derived Cardiomyocytes for Cardiotoxicity Prediction
Stoelzle S, Haythornthwaite A, Kettenhofen R, Kolossov E, Bohlen H, George M, Brüggemann A, Fertig N.
J Biomol Screen. 2011 Jul 20. [Epub ahead of print]
Image from the paper:
Download the full paper here (700 kB) |
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins
David Shaya, Mohamed Kreir, Rebecca A. Robbins, Stephanie Wong, Justus Hammon, Andrea Brüggemann, and Daniel L. Minor, Jr
PNAS Early Edition, 2011, 1 - 6
Screenshot from the paper:
Download the PDF-file (520 kB) |
User Publication: 'Pharmacological studies of Cav3.1 T-type calcium channels using automated patch-clamp techniques'
Kee-Hyun Choi, Chiman Song, Chan S. Cheong and Hyewhon Rhim
Gen. Physiol. Biophys., 2011, 30, 100–105
Download PDF-File (368 kB) |
User Publication: 'Chemical and biological characterization of four new linear cationic a-helical peptides from the venoms of two solitary eumenine wasps'
Marisa Rangel, Marcia Perez dos Santos Cabrera, Kohei Kazuma, Kenji Ando, Xiaoyu Wang, Manabu Kato, Ken-ichi Nihei, Izaura Yoshico Hirata, Tyra J. Cross, Angélica Nunes Garcia, Eliana L. Faquim-Mauro, Marcia Regina Franzolin, Hiroyuki Fuchino, Kanami Mori-Yasumoto, Setsuko Sekita, Makoto Kadowaki, Motoyoshi Satake, Katsuhiro Konno
Toxicon 2011, 57,1081–1092
Download PDF-File (1.010 kB) |
Book chapter: 'Cardiac Toxicity'
Ralf Kettenhofen and Silke Schwengberg
ADMET for Medicinal Chemists: A Practical Guide, Edited by Katya Tsaioun and Steven A. Kates, John Wiley & Sons, Inc., 2011, 287 - 314 |
User Publication: 'Development of a selective small-molecule inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel'
Gautam Bhave1, Brian A. Chauder1, Wen Liu2, Eric S. Dawson1, Rishin Kadakia1, Thuy T. Nguyen1, L. Michelle Lewis1, Jens Meiler1, C. David Weaver1, Lisa M. Satlin2, Craig W. Lindsley1 and Jerod S. Denton1,
Molecular Pharmacology, 2011, 79(1), 42-50 |
|
