Nanion Technologies

Orbit 16

Instant bilayers - just add protein.

Bilayer recording typically means tedious waiting for bilayer formation, protein introduction and eventually ion channel activity. The Orbit platforms take the pain out of bilayer recordings and enables fast and successful data generation thanks to the rapid formation of multiple bilayers and parallel recordings.

The Orbit 16 supports:

- Automated formation of 16 bilayers at the push of a button

- Low noise, high bandwidth recordings

- Substantial data generation through 16 fully parallel recordings

Orbit 16The Orbit 16 is equipped by default with the Elements e16 amplifier which allows for the fully parallel recording of all 16 channels at highest bandwidths and excellent signal-to-noise ratios. Furthermore, most commercially available amplifiers are compatible with the Orbit 16, including the 16-channel Triton amplifier from Tecella. For single channel amplifiers like the EPC-10 or Axopatch, the Orbit has a built-in multiplexer switchboard, allowing for recordings from the individual bilayers by automatically switching through the recording sites.

MECA – Micro Electrode Cavity Array 

A complete Orbit 16 platform consists of the main recording station, an amplifier (plus optional switchboard unit) and a recording module supporting Ionera's1 MECA 16-chips.

MECA-chipThe MECA recording substrate contains a 4 x 4 array of circular microcavities in a highly inert polymer. Each cavity contains an individual integrated Ag/AgCl-microelectrode. The bilayer is automatically formed by remotely actuated painting (Ionera1-SPREAD), thus roofing the liquid-filled cavity.

[1] Ionera (www.ionera.de), a spin-off from the University of Freiburg, Germany, will be the OEM for the MECA (microelectrode cavity array) chip.

 

Downloads:

Orbit 16 Product Sheet