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    Nanion Technologies: Smart Tools for Ion Channel Research

  • SyncroPatch 384i: HTS Automated Patch Clamp

    SyncroPatch 384i: HTS Automated Patch Clamp

  • SURFE²R 96SE: Label-free HTS Transporter Screening

    SURFE²R 96SE: Label-free HTS Transporter Screening

  • Dynamic Clamp: Patchliner

    Dynamic Clamp: Patchliner

  • Bilayer recordings: Orbit product family

    Bilayer recordings: Orbit product family

  • CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

    CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

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SyncroPatch 384i

SyncroPatch 384i

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Patchliner

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CardioExcyte 96

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FLEXcyte 96

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SURFE²R N1

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Orbit 16

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Vesicle Prep Pro

2019 - FLEXcyte: A New In Vitro Tool to Study Cardiac Contractility under Physiological Mechanical Conditions

 Icon FLEX   FLEXcyte 96 poster, Nanion User Meeting USA 2019  logo pdf   (0.4 MB)

Abstract:

Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. Integration into standard lab procedures remains a challenge for current in vitro systems. The FLEXcyte 96 system has the potential to scale-up mechanical testing towards medium-throughput analyses. We show here that, using stem cell-derived cardiomyocytes, this system enables predictive recordings of contractile behavior in the presence of well-known reference compounds.

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