2011 - Cardiac Toxicity

   Patchliner and      Port-a-Patch book chapter in ADMET for Medicinal Chemists: A Practical Guide (2011)

Authors: 
Kettenhofen R., Schwengberg S.

Book chapter:
ADMET for Medicinal Chemists: A Practical Guide, Edited by Katya Tsaioun and Steven A. Kates, John Wiley & Sons, Inc. (2011) 287 - 314

Keywords: 

• cardiac toxicity and nonarrhythmic cardiac toxicity;
• preclinical models for assessment - of ion channel-related cardiotoxicity;
• pluripotent stem cell-derived cardiomyocytes - either from mouse or human origin, promising cellular models combining cell line advantages

Download here

Back to Overview