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2020 - Elevated myocardial SORBS2 and the underlying implications in leftventricular noncompaction cardiomyopathy

Icon CE   CardioExcyte 96 publication in EBioMedicine (2020)

Authors:
Li C., Liu F., Liu S., Pan H., Du H., Huang J., Xie Y., Li Y., Zhao R., Wei Y.

Journal:
EBioMedicine (2020) doi: 10.1016/j.ebiom.2020.102695


Abstract:

Left ventricular noncompaction cardiomyopathy (LVNC) is a hereditary heart disease characterized by an excessive trabecular meshwork of deep intertrabecular recesses within the ventricular myocardium. The guidelines for management of LVNC patients aim to improve quality of life by preventing cardiac heart failure. However, the mechanism underlying LVNC-associated heart failure remains poorly understood.


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