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    CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

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2021 - Long noncoding RNA VENTHEART is required for cardiomyocyte specification and function

icon sp96 CardioExcyte 96 pre-print publication in bioRxiv (2021)

Authors:
Dashi A., Tan W.L.W., Anene-Nzelu C.G., Pan B., Ilmari A.M., Tiang Z., Hartman R.J.G., Stenzig J., Wei H., Gao Bin C., Ackers-Johnson M.A., Lim B., Walentinsson A., Iyer V.V., Jonsson M.K.B., Foo R.S.

Journal:

bioRxiv (2021) doi: 10.1101/2021.02.01.429136


Abstract: 

Long noncoding RNAs (lncRNAs) control cardiac gene expression during heart development and disease. It is accordingly plausible for the same lncRNA to regulate both cardiac development, as well as play a role in adult heart disease progression. lncRNA regulators of early cardiomyocyte (CM) lineage commitment have been identified and characterised, however those controlling later CM specification remain unknown.


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