• Nanion Technologies: Smart Tools for Ion Channel Research

    Nanion Technologies: Smart Tools for Ion Channel Research

  • SyncroPatch 384i: HTS Automated Patch Clamp

    SyncroPatch 384i: HTS Automated Patch Clamp

  • SURFE²R 96SE: Label-free HTS Transporter Screening

    SURFE²R 96SE: Label-free HTS Transporter Screening

  • Dynamic Clamp: Patchliner

    Dynamic Clamp: Patchliner

  • Bilayer recordings: Orbit product family

    Bilayer recordings: Orbit product family

  • CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

    CardioExcyte 96 SOL: Pacing Cardiomyocytes with Light

Our Product Portfolio

SyncroPatch 384

SyncroPatch 384

Patchliner

Patchliner

Port-a-Patch

Port-a-Patch

Port-a-Patch mini

Port-a-Patch mini

CardioExcyte 96

CardioExcyte 96

FLEXcyte 96

FLEXcyte 96

SURFE²R 96SE

SURFE²R 96SE

SURFE²R N1

SURFE²R N1

Orbit 16 TC

Orbit 16 TC

Orbit Mini

Orbit Mini

Vesicle Prep Pro

Vesicle Prep Pro

Buffer Solution

Buffer Solution

Vesicle Prep Pro - Liposomes made easy


The Vesicle Prep Pro is the first product on the market for automated preparation of solvent-free giant unilamellar vesicles (GUVs). The GUVs are formed by means of electro-swelling. The benefits the Vesicle Prep Pro offers include:

  • GUVs of homogeneous size (1 - 30 μm in diameter)
  • Temperature control
  • Adjustable parameters (temperature; current amplitude; frequency)
  • Variety of lipids can be used
  • Ideal for bilayer recordings and protein measurements
  • Stable and reproducible GUVs
  • Reusable ITO slides

The Vesicle Prep Pro has been designed to keep the preparation process simple. This ensures stable and reproducible results.

The chamber in which the GUVs are made is formed by ITO-coated glass cover slides so that vesicle formation can be monitored using a microscope.

Integrated features, including flexible protocol design and temperature control, allow generation of GUVs from a wide variety of lipids, e.g. lipids with high charge or high phase transition temperatures.

GUVs prepared with the Vesicle Prep Pro have proven ideal for investigations of biophysical properties of e.g. electrogenic transmembrane proteins, lipid raft formation, and protein-DNA interactions.

For detailed information:

VesicleControl: Software

VesicleControl: Software for the Vesicle Prep Pro device

VesicleControl big

Using VesicleControl, complex protocols for the Vesicle Prep Pro can be defined and visually inspected. Control of parameters such as voltage amplitude, frequency, temperature and time allow very flexible protocol design for the production of homogeneously-sized vesicles. In particular, due to the control over the temperature, it is possible to generate vesicles of homogeneous lipid distribution using lipids with different phase transition temperatures.

Buffers and Solutions

Buffers and Solutions for the Vesicle Prep Pro

The buffers and solutions for the Vesicle Prep Pro are produced by Nanion and an external partner, quality-assured in-house at Nanion headquarters and shipped from Munich to our international customers.


Available buffers and solutions
  • "Vesicle Prep Pro GUV Kit": 5 vials x 500 µL GUVs, 13x 100 mM HCl, 9x 1 mL Sorbitol, 1 mM EGTA, 2 mM HEPES (pH 7.0 KOH); 13x 200 mM KCl, 10 mM HEPES (pH 7.0 KOH); 14x 200 mM KCl, 10 mM Hepes (pH 4.0 KOH), 13x 200 mM NaCl, 10 mM Hepes (pH 7.0 NaOH); 14 x 200 mM NaCl, 10 mM Hepes (pH 4.0 NaOH) (Order # 051003)

Testimonials & Case Studies

Data and Applications

Downloads:

Application Notes

Product Sheets

Publications

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