Patchliner publication in Frontiers in Physiology (2019)
Red Blood Cell Membrane Conductance in Hereditary Haemolytic Anaemias.
Patchliner publication in CNS Neuroscience & Therapeutics (2019)
Discovery of a small molecule modulator of the Kv1.1/Kvβ1 channel complex that reduces neuronal excitability and in vitro epileptiform activity
Patchliner publication in Journal of Chemoinformatics (2019)
Avoiding hERG-liability in drug design via synergetic combinations of different (Q)SAR methodologies and data sources: a case study in an industrial setting
Patchliner publication in ACS Medicinal Chemistry Letters (2019)
Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs
Patchliner publication in Cell Stem Cell (2019)
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
Patchliner publication in HemaSphere (2018)
A Previously Unrecognized Ca2+-inhibited Nonselective Cation Channel in Red Blood Cells
Patchliner publication in Toxicology Letters (2018)
Counteracting desensitization of human α7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning
Patchliner publication in PNAS (2018)
Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death
Patchliner publication in Pharmacological Research (2018)
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo.
Patchliner publication in Frontiers in Physiology (2018)
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of IK1 Ion Channels in Real-Time
Patchliner and SyncroPatch 384/768PE publication in Expert Opinion on Drug Discovery (2018)
An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery.
Patchliner publication in British Journal of Pharmacology (2017)
Correlation between human ether-a-go-go related gene channel inhibition and action potential prolongation.
Patchliner publication in Traffic (2017)
14-3-3 proteins regulate K2P5.1 surface expression on T lymphocytes.
Patchliner publication in Cellular Physiology and Biochemistry (2017)
Trifluoperazine-Induced Suicidal Erythrocyte Death and S-Nitrosylation Inhibition, Reversed by the Nitric Oxide Donor Sodium Nitroprusside.
Patchliner publication in Scientific Reports (2017)
'Gardos Channelopathy': a variant of hereditary Stomatocytosis with complex molecular regulation.
Patchliner publication in Human Mutation (2017)
Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.
Patchliner publication in Frontiers in Pharmacology (2017)
Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function.
Patchliner publication in Annals in Neurobiology (2017)
Myoclonus Epilepsy and Ataxia due to KCNC1 Mutation: Analysis of 20 Cases and K+ Channel Properties.