Publications
Port-a-Patch,
Patchliner and
SyncroPatch 96 publication in Expert Opinion on Drug Discovery (2012)
HTS techniques for patch clamp-based ion channel screening - economy and advances.
Patchliner publication in Frontiers in Pharmacology (2012)
Toward a new gold standard for early safety: automated temperature-controlled hERG test on the Patchliner.
Patchliner publication in Journal of Biological Chemistry (2011)
The Chimeric approach reveals that differences in the TRPV1 pore domain determine species-specific sensitivity to block of heat activation.
Patchliner and
Port-a-Patch publication in Journal of Biological Chemistry (2011)
Automated Patch Clamp on mESC-Derived Cardiomyocytes for Cardiotoxicity Prediction.
Patchliner and
Port-a-Patch book chapter in ADMET for Medicinal Chemists: A Practical Guide (2011)
Chapter: Cardiac Toxicity.
Patchliner publication in Molecular Pharmacology (2011)
Rapid and Contrasting Effects of Rosiglitazone on Transient Receptor Potential TRPM3 and TRPC5 Channels.
Port-a-Patch,
Patchliner and
SyncroPatch 96 publication in Frontiers in Pharmacology (2011)
State-of-the-art automated patch clamp devices: heat activation, action potentials, and high throughput in ion channel screening.
Patchliner publication in General Physiology and Biophysics (2011)
Pharmacological studies of Cav3.1 T-type calcium channels using automated patch-clamp techniques.
Patchliner and
SyncroPatch 96 publication in Frontiers in Pharmacology (2011)
Automated electrophysiology makes the pace for cardiac ion channel safety screening.
Patchliner publication in Molecular Pharmacology (2011)
Development of a selective small-molecule inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel.
Port-a-Patch,
Patchliner and
SyncroPatch 96 publication in Future Medical Chemistry (2010)
Renaissance of ion channel research and drug discovery by patch clamp automation.
Port-a-Patch publication in Proc. Natl. Acad. Sci. USA. (2010)
Multiplexed transposon-mediated stable gene transfer in human cells.
Patchliner publication in Bioorganic & Medical Chemistry (2010)
Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae.
Port-a-Patch and
Patchliner publication in Lonza Resource Notes (2010)
Cor.At Cardiomyocytes: Primary-like Cardiomyocytes for Manual and Automated Electrophysiological Screening.
Patchliner publication in Circulation Research (2010)
Pregnenolone Sulphate- and Cholesterol-Regulated TRPM3 Channels Coupled to Vascular Smooth Muscle Secretion and Contraction.
Patchliner publication in Frontiers in Pharmacology (2010)
Propranolol blocks cardiac and neuronal voltage-gated sodium channels.
Port-a-Patch and
Patchliner publication in Combinatorial Chemistry & High Throughput Screening (2009)
Port-a-Patch and Patchliner: High fidelity electrophysiology for secondary screening and safety pharmacology.
Patchliner publication in Frontiers in Molecular Neuroscience (2009)
High throughput techniques for discovering new glycine receptor modulators and their binding sites.
Patchliner publication in Molecular Pharmacology (2009)
High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.
Patchliner publication in Nature Protocols (2009)
Robotic multiwell planar patch-clamp for native and primary mammalian cells.