SyncroPatch 384PE publication in Research in Veterinary Medicine (2019)
Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel Kv11.1.
SyncroPatch 384PE publication in Cell (2019)
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
SyncroPatch 384PE publication in Molecules (2019)
Aptamer Efficacies for In Vitro and In Vivo Modulation of αC-Conotoxin PrXA Pharmacology.
SyncroPatch 384PE publication in Bioorganic and Medicinal Chemistry (2019)
Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3.
SyncroPatch 384PE publication in Bioorganic and Medicinal Chemistry Letters (2019)
Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903.
SyncroPatch 384PE publication in European Journal of Pharmacology (2019)
Electrophysiological evaluation of pentamidine and 17-AAG in human stem cell-derived cardiomyocytes for safety assessment.
Patchliner, SyncroPatch 384PE and CardioExcyte 96 publication in Channels (2015)
Novel screening techniques for ion channel targeting drugs.
SyncroPatch 384PE publication in Circulation: Genomic and Precision Medicine (2018)
High-Throughput Functional Evaluation of KCNQ1 Decrypts Variants of Unknown Significance.
SyncroPatch 384PE publication in Haematologica (2018)
A Novel Gain-Of-Function Mutation Of Piezo1 Is Functionally Affirmed In Red Blood Cells By High-Throughput Patch Clamp.
SyncroPatch 384PE book chapter in Phenotypic Screening (2018)
Developing High-Throughput Assays to Analyze and Screen Electrophysiological Phenotypes.
SyncroPatch 384PE publication in IFSCC (2018)
Towards Novel Bioactive Antiperspirants for Cosmetic Applications.
SyncroPatch 384PE related publication in the International Journal of Cardiology
Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D).
SyncroPatch 384PE article in The Surfaceome (2018)
NaV Channels: Assaying Biosynthesis, Trafficking, Function.
SyncroPatch 768PE publication in PNAS (2018)
Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors.
SyncroPatch 384/768PE and Patchliner publication in Expert Opinion on Drug Discovery (2018)
An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery.
SyncroPatch 768PE publication in Neurology Genetics (2017)
Characterization of a KCNB1 variant associated with autism, intellectual disability, and epilepsy
SyncroPatch 768PE publication in PLoS One (2017)
High-throughput electrophysiological assays for voltage gated ion channels using SyncroPatch 768PE.
SyncroPatch 768PE publication in Nature Communications (2017)
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions.
Patchliner and SyncroPatch 384PE book chapter in Stem Cell-Derived Models in Toxicology (2017)
Automated Patch Clamp Recordings of Human Stem Cell- Derived Cardiomyocytes.
SyncroPatch 384PE publication in Molecular Pharmacology (2016)
Use-dependent Block of Human Cardiac Sodium Channels by GS967.