• ENaC

    Cumulative dose-dependent block of ENaC by Amiloride, measured on the SyncroPatch 96, a predecessor model of the SyncroPatch 384PE

ENaC - Epithelia Sodium Channel Analysis

SP96 Enac Amiloride

icon sp96   SyncroPatch 96 (a predecessor model of SyncroPatch 384PE) data and applications:

The data present cumulative dose-dependent block of ENaC by Amiloride. Currents were obtained performing ramps -100mV/100mV every 2 s from a Vhold=-40mV. The large window shows the effect of increasing concentrations (1 µM, 10µM, 100µM) of Compound on the ENaC currents. The IC50 with Amiloride was 2.3 µM. Data were collected with a success rate of ~70 %.

 

Back to Overview

 

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.