• GABAA a1b3g2

    Pharmacology on GABAA α1β3γ2 as recorded on a multihole (4x) plate (measured on the SyncroPatch 96, a predecessor model of the SyncroPatch 384PE

GABAA Receptor (a1b3g2) - Antagonists

GABAa1 Antagonists

icon sp96   SyncroPatch 96 (a predecessor model of SyncroPatch 384PE) data and applications:
Cells were kindly provided by Millipore.

Pharmacology on GABAA α1β3γ2 as recorded on a multihole (4x) plate. Mean concentration response curves for Bicuculline, IC50 = 470 nM (n = 14); for a5IA IC50 = 461.19 pM (n = 9), maximum block was 29% at 100 nM; for FG7142 IC50= 54.52 nM (n = 15), maximum block was 58% at 10 μM; for MRK016 maximum current inhibition was 44.8% at 1 uM, IC50= 5.98 nM (n = 11). 

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