• GlyR a1

    Glycine-mediated current traces and corresponding time plots, measured on the SyncroPatch 384PE

Glycine Receptor (GlyRa1) - Pharmacology

p20 3 hGlyRalpha1icon pap   Port-a-Patch data and applications:
Cells were kindly provided by AstraZeneca, Sweden.

The Laminar Flow Chamber can also be used for studying glycine receptors. The pharmacology of the hGlyRα1, expressed in a mouse fibroblast cell line (L-tk), was investigated. The EC50 for glycine was determined as 89 ± 2.7 μM (n = 10) which is in accordance with the literature.

 

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