Glycine Receptor (GlyRa1 & GlyRa3) - Dose Response Analysis

   Patchliner data and applications:

(A) Effects of indicated concentrations of 3 on α1 and α3 GlyR currents activated by EC₂₀ glycine concentrations as indicated. Unfilled bars denote glycine applications and filled bars denote compound applications. (B & C) Average dose response curves of 3 at α1 and α3 GlyRs, respectively.
Data are taken from Balansa W. et al., Bioorg Med Chem. 2010 Apr 15;18(8):2912-9.

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