hERG - Temperature Control

DATA Temp Control small

icon pap   Port-a-Patch data and applications:
Cells were kindly provided by Cytomyx/Millipore.

The image shows example traces for hERG mediated currents at 25 ± 2 °C (black) and 35 ± 2 °C (blue). The peak current amplitude was increased at 35 °C, and the rise time and decay time constants were faster at physiological temperature compared with those obtained at room temperature. 

 

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