NaV1.5 - Lidocaine Block
Patchliner data and applications:
Cells were kindly provided by Cytomyx/Millipore.
Full dose response curves at different holding potentials were recorded for each cell (hNav1.5 in HEK293). Currents were elicited by a 10 ms voltage step to 0 mV. Plotted are average peak currents as a function of holding potential and lidocaine concentration.