• PepT1

    Representive traces of PepT1 overexpressed in CHO cells, measured on the SURFE²R N1. The PepT1 signal is evoked by glycylglycin and inhibited by addition of Lys[Z(NO2)]-Val.

PepT1 - Pharmacology of Losartan

Surfer N96 PepT1 Losarthan IC50 datacontrolIcon 96SE   SURFE2R N96 (a predecessor model of SURFE²R S96) data and applications:

Transport by PepT1 is inhibited by the kompetitive antagonist Losartan. When activated with 20 mM Gly-Gly, the IC50 of Losartan was 80.4 µM. Data were analysed with DataControl - the Analysis software tool for recordings on the SURFE2R N96 and SyncroPatch 96/ 384PE.

 

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