• Piezo1

    Piezo1 expressed in Neuro2A cells activated by Yoda1 on the SyncroPatch 384PE.

    Data from Rotordam et al, 2019.

Piezo1 in red blood cells - Hereditary Xerocytosis

Piezo1 RBC Syncroicon sp96   SyncroPatch 384PE (a predecessor model of the SyncroPatch 384) data and applications:

Whole-cell recordings of ion currents from RBCs of healthy donors and Hereditary Xerocytosis patients. Different mutations in the PIEZO1 gene were compared with controls. Aa The P50.2 mutation resulted in current conductance that was unchanged compared with transport controls, but showed increased conductance compared with general controls (Ab). The mutation P52.1 showed decreased conductance compared with transportation controls (Ba) and general controls (Bb).

Data from Petkova-Kirova et al, 2019.

 

 

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