TRIC-A / TRIC-B | Trimeric Intracellular Cation Channel Type A / B
Trimeric Intracellular Cation Channels, also known as TMEM38 family
2 members: TRIC-A, TRIC-B
Each TRIC subunit contains three transmembrane domains, a cytoplasmic C-terminus and a luminal N-terminus. Functional entities are formed by homotrimerizarion.
Modulate the release of Ca2+ through the ryanodine receptor or inositol triphosphate receptor, and maintain the homeostasis of ions within sarcoplasmatic and endoplasmatic lumen