TRPA1 - Inhibition by A967079 and AMG0902

  SyncroPatch 384i (a predecessor model of the SyncroPatch 384) data and applications: 
Cells were kindly provided by AcCELLerate.

Inhibition of TRPA1 by A967079 and AMG0902. A TRPA1-mediated responses were blocked by A967079 in a concentration-dependent manner with an IC₅₀ value (12.4 nM) in good agreement with the literature value of 50 nM. B TRPA1-mediated responses were blocked by AMG0902 in a concentration-dependent manner with an IC₅₀ value of 48 nM (n = 349) in good agreement with the literature value of 68 nM.

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