TRPM8 and Temperature Control

icon sp96   PE384 TRPM8SyncroPatch 384 data and applications:
Cells were kindly provided by Charles River Chantest

At RT, the TRPM8 current was activated using increasing concentrations of Menthol (left). Measurement site, cells and solutions can be accurately temperature controlled – in the presence of temperatures 38°C, 25°C, 18°C and 12 °C the current size of temperature regulated TRPM8 changes accordingly (right). TRPM8 is activated at temperatures < 25°C.


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