Port-a-Patch application note: (0.6 MB)
Cells were kindly provided by Axiogenesis.
To provide scientists in basic or applied cardiology and toxicology with a standardized and pure cardiac myocyte model with functional expression of all essential cardiac ion channels, Axiogenesis has developed Cor.At® cardiomyocytes. These mouse embryonic stem cell derived cardiomyocytes are ready to use and 99.9 % pure without contamination by other cell types. Using the Porta-Patch®, Cor.At® cardiomyocytes have experimentally been shown to functionally express at least three essential cardiac currents INa, ICa, and IK, and to exhibit typical cardiac action potentials.