Nanion Corporate Blog


20.12.2017: New SyncroPatch 768PE paper published in Neurology Genetics

Title: "Characterization of a KCNB1 variant associated with autism, intellectual disability, and epilepsy"

Scientists at Northwestern University have identified a KCNB1 variant associated with a neurodevelopmental disorder which causes a partial loss of function of the KV2.1 channel. Using the SyncroPatch 768PE, a shift in the voltage dependence of activation was observed in the variant compared with wild type channels which results in a reduced availability of the channel. 

Download the full paper here.

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