Nanion Corporate Blog


10.01.2018: New SyncroPatch 768PE paper published in PNAS

Title: "Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors"

Scientists at Genentech and Xenon have worked together to propose a new mechanistic approach using patch clamp electrophysiology to identify NaV1.7 selective compounds. By using a pore mutant of NaV1.7 and using the SyncroPatch 768PE, the scientists were able to identify NaV1.7 selective compounds acting via other mechanisms than pore blocking.

Download the full paper here.

Back to Overview

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.