Nanion Corporate Blog

 

22.01.2018: New publication featuring CardioExcyte 96 data in Journal of Molecular and Cellular Cardiology

Title: "Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes"

Bjorn Knollmann and colleagues have introduced a mutation in cardiac troponin (TnT-I79N) into human induced pluripotent stem cells to create a model of hypertrophic cardiomyopathy. The CardioExcyte 96 was used to confirm the effects of this mutation on pro-arrhythmic changes in the human ventricular action potentials. 

Download the full paper here.

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