13.11.2020 - A deep-dive into ClC: Chloride/Proton Exchanger
ClC - Chloride/Proton Exchanger
The Chloride Carrier/Channel Family is a large but poorly understood family consisting of several hundred sequenced proteins from bacteria and eucaryotes. Although structurally similar, the individual proteins act either as chloride channels or as chloride/proton exchangers. Most CIC proteins are located in the plasma membrane, but several are predominantly in intracellular membranes.
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Here we present Ec-ClC activity measurements on the SURFE2R N1 instrument using proteoliposomes reconstituted with purified Ec-ClC at different lipid-to-protein ratios:
Watch this On-Demand Presentation to learn how Dr. Matthias Quick is using SURFE2R Technology to investigate Membrane Transporters: