Nanion Corporate Blog


13.05.2021: Research Ins]i[ghts: Cardiac Safety Symposium 2021 - Session 3

Session 3 - Electrophysiology Data and in-silico Modelling (the third of four sessions across our two-day event)

Selected Publications

2020 - Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

2020 - A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

2020 - A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model

Interested in further CiPA reading?

Adam Hill
PhD, Head Computational Cardiology, Victor Chang Cardiac Research Institute
Title: An automated, cloud-based platform for quality control, data analysis and risk prediction of inherited and drug-induced arrhythmias
[1:05 PM - 1:30 PM CEST]

Jessica Veenman-Koepke

Scientist & Project leader at Ncardia
Title: Multi-parametric Drug Safety Assessment in Bioreactor-produced Ncyte hiPSC-derived Cardiomyocytes
[1:30 PM - 1:40 PM CEST]

Gary Mirams
Professor of Mathematical Physiology, University of Nottingham
Title: Examining temperature dependence of hERG1a gating
[1:40 PM - 2:05 PM CEST] 

Teun de Boer
Associate Professor, UMC Utrecht
Title: Building hybrid biological-digital twins of cardiomyocytes using dynamic clamping

[2:05 PM - 2:30 PM CEST]

[2:30 PM - 2:45 PM CEST]

Register for the Event

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