Nanion Corporate Blog

 

14.05.2021: Research Ins]i[ghts: Cardiac Safety Symposium 2021 - Session 4

Session 4 - Best Practices and Evolvements of Safety Pharmacology Methods (the last session across our two-day event)



Selected Publications

2020 - Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations

2020 - Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment

2020 - Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective


 James Kramer,
Principal Scientist, Charles River Laboratories
Title: ICH S7B Q&As - Best Practices for Ion Channel Assays
[2:45 PM - 3:10 PM CEST]

Michael K. Pugsley, PhD, FBPhS, DSP 
Cytokinetics
Title: A 20 Year Journey through the Continuously Evolving Role of Safety Pharmacology in Drug Safety Evaluation
 [3:10 PM - 4 PM CEST]

Al George
Professor and Chair of Pharmacology, Northwestern University
Title: Automated Patch Clamp to Assess Sodium Channel Blocker Effects on hiPSC-derived Cardiomyocytes
[4:00 PM - 4:25 PM CEST]

ROUND TABLE DISCUSSION
[4:25 PM - 4:45 PM CEST]

Register for the Event

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