Nanion Corporate Blog

 

09.09.2021: NEW! Contractile Force measurements in 96-well format with FLEXcyte 96



 

Contractile Force quantification is an important prerequisite for applications of human iPSC-CMs in disease modeling and drug screens.

Therefore, we included a Contractile Force calculation in our FLEXcyte 96 system by correlating the membrane movement with the tension of the cell-substrate-complex (mN/mm2) for each recording well.

We previously could show functional maturation of iPSC-CMs with physiological responses such as a positive force-frequency behavior or positive inotropic responses after application of Omecamtiv Mecarbil. But, with our new online analysis parameter, it's now possible to quantify the actual contractile force generation of cells!

Request your FLEXcyte 96 demo (online or live)

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