Nanion Corporate Blog

 

07.10.2021: FLEXcyte 96 Contractile Force Analysis 

FLEXcyte 96 Contractile Force Analysis 

Contractile Force quantification is an important prerequisite for applications of human iPSC-CMs in disease modeling and drug screens.

Therefore we included a Contractile Force calculation in our FLEXcyte 96 system, by correlating the membrane movement with the tension of the cell-substrate-complex (mN/mm2) for each recording well.

We previously could show functional maturation of iPSC-CMs with physiological responses such as a positive force-frequency behavior or positive inotropic responses after application of Omecamtiv Mecarbil. With our online analysis it's possible to quantify the actual contractile force generation of cells!
phocathumbnail Nanion Poster SURFE²R CardioExcyte96 SPS 2018
Learn more about contractile force analysis in this flyer

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