07.10.2021: FLEXcyte 96 Contractile Force Analysis
FLEXcyte 96 Contractile Force Analysis
Contractile Force quantification is an important prerequisite for applications of human iPSC-CMs in disease modeling and drug screens.
Therefore we included a Contractile Force calculation in our FLEXcyte 96 system, by correlating the membrane movement with the tension of the cell-substrate-complex (mN/mm2) for each recording well.
We previously could show functional maturation of iPSC-CMs with physiological responses such as a positive force-frequency behavior or positive inotropic responses after application of Omecamtiv Mecarbil. With our online analysis it's possible to quantify the actual contractile force generation of cells!
Learn more about contractile force analysis in this flyer