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30.09 - 03.10.2018 | Annual Meeting of the Safety Pharmacological Society (SPS)

180930 event image SPS
Conference Venue
: Marriott Wardman Park, 2660 Woodley Rd NW, Washington, DC 20008, USA

Go to the Conference website here.

Visit us at our booth #404

and meet our team from Nanion Technologies USA (Rodolfo Haedo and George Okeyo), Germany (Sonja Stölzle-Feix) and Japan (Atsushi Ohtsuki).


Attend our workshop:

  • Title: "Cell and In Vitro Practices for Effectively Leveraging Cellular Functional Assays: An HTS Overview"
  • Monday, October 1, 18:00 - 19:00 PM
  • Meeting Room: Hoover

Confirmed Speakers:

  • Dr. Sonja Stölzle-Feix,
    Nanion Technologies, Germany
  • Dr. Sami Noujaim, Associate Professor, Director, Cardiac Electrophysiology Research
    University of South Florida, USA
    Title: "Antiarrhythmic Potential of Antimalarial Aminoquinolines"
    Download the abstract here.
  • Dr. James Kramer, Principal Scientist
    Charles River, USA
    Title: "Late-Nav1.5 Current Inhibition Successfully Evaluated in High Throughput Automated Ion Channel Patch Platforms but Choice of Agonist Is Important"
    Download the abstract here.
  • Dr. Matthias Gossmann, CEO
    innoVitro, Germany
    Title: "CardioExcyte 96 Goes Flexible: Investigating Cardiac Contractility under Physiological Mechanical Conditions with the CellDrum Add-On"
    Download the abstract here

Attend the workshop of FUJIFILM Cellular Dynamics, Inc.:

  • Presented by: FUJIFILM Cellular Dynamics, Inc. and Nanion Technologies GmbH
  • Title: "Implementing Human iPSC-Derived Cells in Early Safety Assessment and Disease Modeling"
  • Tuesday, October 2, 12:30 – 1:30 pm
  • Meeting Room: Hoover

Speakers:

  • T.K. Feaster, Ph.D. Product Manager, FUJIFILM Cellular Dynamics, Inc.
  • Sonja Stölzle-Feix, Ph.D. Director, Scientific Affairs,Nanion Technologies 

Part I: 12:30 PM – 12:45 PM: Dr. T.K. Feaster will discuss the predictive power of human iPSC-derived cells for in vitro toxicity testing. He will highlight toxicology, drug screening, and disease models. Demonstrating increased functionality and throughput valuable for identifying liabilities early in preclinical safety programs.

Part II: 12:50 PM – 1:20 PM: Dr. Sonja Stoelzle-Feix will discuss the effects of “CiPA drugs” on excitation-contraction coupling in iCell Cardiomyocytes^2. She will describe the evaluation of the proarrhythmic potential of 23 blinded drugs on hiPSC-CMs using iCell CM2 and the CardioExcyte 96 at different sites. Ion channel data and myocyte behaviour will be discussed and aligned.


We are presenting the following posters:

  • Poster # 0025
    Title: "Safety Pharmacology measurements within the CiPA initiative using automated Patch Clamp"
    Download the poster abstract here.
  • Poster # 0041
    Title: "Introducing Simulated IK1 into Human iPSC-Cardiomyocytes Using Dynamic Clamp on an Automated Patch Clamp System"
    Download the poster abstract here.

  • Poster # 0042
    Title: "A Sensor Based Technique for Pharmacological Safety Testing of Cardiac Transport Proteins NCX, NaKATPase and Respiratory Chain Complexes"
    Download the poster abstract here.
  • Poster # 0188
    Title: "Bridging HTS Ion Channel and Myocyte Data"
    Download the poster abstract here.

The following collaborative poster is presented by innoVitro:

  • Poster # 0166
    Title: "A New In Vitro Tool to Investigate Cardiac Contractility under Physiological Mechanical Conditions"
    Download the poster abstract here.

More information is coming soon. Subscribe to our Newsletter to keep you updated.

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