Nanion Webinars


June 2021 - Channelopathies resolved via cryo-EM and X-ray crystallography: an investigation of muscle excitation-contraction coupling

210629 June Webinar 1200x627 Leaderboard background Filip RyR Webinar

Presenters: 

Dr. Filip Van Petegem, Professor, Biochemistry and Molecular Biology 
(University of British Columbia)

Abstract: 

Muscle contraction requires a tight communication between Ca2+-permeable ion channels located in the plasma membrane (L-type calcium channels, CaVs ) and in the Sarcoplasmic Reticulum (Ryanodine Receptors, RyRs).  In cardiac muscle, Ca2+ entering through CaV1.2 can stimulate the nearby RyR2 isoform, through a process of Ca2+-induced Ca2+ release.  In skeletal muscle, however, the coupling is thought to occur mechanically, with voltage-dependent conformational changes in CaV1.1 being transmitted to RyR1, either through direct or indirect interactions.  Mutations in RyR1 (as well as CaV1.1) can give rise to malignant hyperthermia (MH), a potentially lethal condition typically triggered by volatile anaesthetics. Other mutations cause central core disease (CCD), whereas some are linked to both MH and CCD.  Similarly, mutations in RyR2 are linked to a form of stress-induced cardiac arrhythmia, known as CPVT (catecholaminergic polymorphic ventricular tachycardia).  Our lab has been solving crystal structures of isolated RyR domains in WT and disease mutant forms, which show that many mutations cause conformational changes. More recently, we solved cryo-EM structures of RyR1 carrying the founding mutation (R615C) that links RyR1 to malignant hyperthermia. The structures show how many mutations can destabilize the closed state, leading to facilitated channel opening.

In addition, RyRs are heavily regulated by kinases (PKA, CaMKII) that can also facilitate channel opening. Excessive phosphorylation of RyRs has been linked to a range of acquired disorders, including atrial fibrillation and arrhythmias during heart failure.  We elucidated how PKA recognizes the cardiac RyR2 via an unusual interface and show that phosphorylation may induce the formation of extra secondary structure elements.

Finally, I will discuss our efforts to understand the mechanical coupling between CaV1.1 and RyR1 in skeletal muscle. STAC3 is a small protein recently shown to be essential for the coupling. We found this protein to interact with a cytosolic loop of CaV1.1 and found that several mutations in STAC3, linked to myopathy, directly affect this interaction and the mechanical coupling.

Dr. Conrad Weichbrodt, Product Manager of the Orbit product family 
(Nanion Technologies)

Abstract: 

Conrad will introduce Nanion’s Orbit devices for experiments on lipid bilayers and briefly explain how the micro electrode cavity array (MECA) consumables can support even unexperienced operators in generating artificial lipid bilayers and performing successive electrophysiological experiments.

Date: 29. June 2021
Time: 8AM PDT, 11AM EDT, 5PM CEST

Register here

July 2021 - SSM-electrophysiology as a Tool for Uncovering Transporter Function

210701 Lars Olga Webinar

Presenters: 

Olga Boudker, Professor of Physiology and Biophysics
(Weill Cornell Medical College)

Lars Jeuken, Professor of Molecular Biophysics,
(Faculty of Biological Sciences, University of Leeds)

Session Abstract: 

Uncovering the substrates and mechanism of a transporter or demonstrating the functionality of a mutant or variant is a crucial aspect of comprehensive transporter research. In session three of the Transporter Webinar Series Olga Boudker talks about structural studies on a glutamate transporter and how SSM-based electrophysiology supported her work. From Lars Jeuken we hear about the electrophysiological characterization of a metal transporter.

Date: 1. July 2021
Time: 4PM CEST, 10AM EDT

Register here

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Monthly Newsletter

Nanion past Webinars

SyncroPatch 384/768PE

11.03.2021 | Webinar: automated patch clamp webinar high throughput functional evaluation of melanocortin and a CiPA based evaluation of proarrhythmic risk

icon sp96  SyncroPatch 384i 

Date: March 11. 2021

210311 SP384 March 11 Webinar CRL UMich V1

Speakers:

Ciria Hernandez, MD, Ph.D
(Assistant Research Scientist  - University of Michigan Life Sciences Institute)

Yuri Kuryshev
(Principal Scientist - Charles River Laboratories)



14.10.2020 | Webinar: Development and validation of ASIC1a ligand-gated ion channel drug discovery assays on automated patch clamp platforms.

icon sp96  SyncroPatch 384i and icon pl Patchliner Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Marc Rogers (Metrion Biosciences; U.K.)


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: Turning Cells into Reagents

 icon pl SyncroPatch 384i Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Oliver Wehmeier (acCELLerate GmbH) and Dr. Tim Strassmaier (Nanion Technologies)

 


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: ICH S7B best practices considerations - New Q&As and Benchmarking best practices

 icon pl Patchliner and  icon sp96 SyncroPatch 384i Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Sonja Stoelzle-Feix (Nanion Technologies)

 


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: Benchmarking best practices and calibration standards for HTS hERG recordings for improved proarrhythmic assessment

 icon pl Patchliner and  icon sp96 SyncroPatch 384i Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Alison Obergrussberger (Nanion Technologies)

 


This is an on-demand webinar from Nan]i[on and Friends 2020.

16.10.2020 | Webinar: Emerging Role of LRRC8 Volume-Regulated Anion Channels in the Skin

 icon sp96 SyncroPatch 384i Webinar

Date: October 16. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Torsten Fauth (BRAIN AG)
Dr. Oliver Rauh (Technical University of Darmstadt)
Giustina Rotordam (Nanion Technologies)


This is an on-demand webinar from Nan]i[on and Friends 2020.

12.10.2020 | Webinar: The Sodium Channel Network Aachen meets the SyncroPatch

icon sp96  SyncroPatch 384i Webinar

Date: October 12. 2020, 2:00 PM CET (8:00 AM EDT)

201012 Blog Image VUM 2020

Speakers: 

Prof. Dr. med. Angelika Lampert (RWTH Aachen University, Institute of Physiology (Neurophysiology))


This is an on-demand webinar from Nan]i[on and Friends 2020.

12.10.2020 | Webinar: From Manual to Automated Planar Patch-Clamp Electrophysiology: Accelerating Drug Discovery Research in Academic Settings

icon sp96  SyncroPatch 384i Webinar

Date: October 12. 2020, 4:00 PM CET (10:00 AM EDT)

201012 Blog Image VUM 2020

Speakers: 

Fernanda Laezza, M.D. Ph.D. | Graduate Program Director & Associate Professor (Department of Pharmacology & Toxicology University of Texas Medical Branch)



This is an on-demand webinar from Nan]i[on and Friends 2020.

12.10.2020 | Webinar: PatchAnalytics

icon sp96  SyncroPatch 384i Webinar

Date: October 12. 2020, 5:00 PM CET (11:00 AM EDT)

201012 Blog Image VUM 2020

Speakers: 

Lei A. Wang | Research Scientist (Stanley Center for Psychiatric Research - Broad Institute of MIT and Harvard)



This is an on-demand webinar from Nan]i[on and Friends 2020.

04.06.2020 | Webinar: Decrypting variants of unknown significance in the channelopathies

icon sp96  SyncroPatch 384i Webinar

Date: June 4. 2020, 4:00 PM CET (10:00 AM EDT)

200506 blog image SyncroPatch Webinar Playback

Speakers: 

Rodolfo Haedo (COO; Nanion Technologies North America)
Dr. Jen Q. Pan (Director, Translational Neurobiology; Broad Institute of MIT and Harvard)
Prof. Al George (Magerstadt Professor and Chair - Department of Pharmacology;  Northwestern University - Feiberg School of Medicine)

20.11.2018 | Webinar: The RELEVANCE of ion channel interplay – Voltage-activated channels in non-excitable cells

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i),   icon pl   Patchliner,   icon pap   Port-a-Patch Webinar

Date: November 20. 2018, 4:00 PM CET (11:00 AM EDT)

181120 event image Relevance project Webinar

The Webinar focuses on the automated patch clamp assay development for the study of red blood cells in health and disease and the RELEVANCE project, an international consortium of 13 partners from academia, diagnostic labs, blood supply centers, and small companies that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood cell function in health and disease. To this end, Nanion contributes assays for the electrophysiological characterization of healthy and patient-derived red blood cells.

12.09.2018 | Webinar: CiPA study: Bridging ion channel and myocyte data

180912 event image CiPAII Webinar

Icon CE   CardioExcyte 96,   icon pl   Patchliner and   icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i) Webinar

Date: September 12, 4:00 PM CEST (10:00 AM EDT)

 Get up-to-date with the CiPA progress of the Myocyte and Ion Channel Work Goups:

  • CiPA myocyte phase II validation study results: cross-site comparison using the CardioExcyte 96
  • HTS Phase I study: an update on progress of the CiPA Ion Channel Work Stream using the SyncroPatch 384PE and Patchliner

08.05.2018 | Webinar: HTS Sodium Ion Channel Assays on the SyncroPatch 384PE

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i)

Learn about Sodium Ion Channel Assays on the SyncroPatch 384PE. Our speakers will present assays on NaV1.1, NaV1.7, NaV1.8 and NaV1.9:

  • Biophysical and Pharmacological Characterization of Voltage-Gated Na Channels Involved in Pain Pathways.
  • Identifying NaV1.1  Enhancers to Restore Inhibitory Interneuron Function in Dravet Syndrome and Alzheimer’s Disease.

03.11.2016 | External Webinar: Accelerating Ion Channel Characterization and New Drug Candidate Identification

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i)

This webinar will show high-throughput functional annotation of human ion channel variants associated with excitation disorders will be described along with use of the Syncropatch 384PE to measure subtype selective activation of KV7 potassium channels as well as inhibition of voltage gated sodium channels like NaV1.7, NaV1.1, and NaV1.5.
Organisation: Icagen Inc.

07.06.2016 | External Webinar: A new analysis capability to improve assessment of cardiac liability in high throughput electrophysiology

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i)

AstraZeneca has implemented the Nanion SyncroPatch 384PE electrophysiology platform. This webinar will show how AstraZeneca and Genedata developed a processing and analysis pipeline for the complex data, reading binary raw data directly from the instrument into Genedata Screener.
Organisation: Genedata AG.

28.07.2015 | Webinar: High Throughput and High Fidelity: Automated Patch Clamp in Screening and Research

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i) and   icon pl   Patchliner 

The webinar covers the use of the Patchliner and the SyncroPatch 384/768PE for characterization of ion channels and screening of ion channel active compounds.

24.10.2013 | Webinar: SyncroPatch 384PE - the PatchEngine. Superior Ion Channel Drug Screening

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i)

The Webinar covers the introduction of the SyncroPatch 384PE and its features.

07.03.2013 | Webinar: Top gear ion channel screening

icon sp96   SyncroPatch 96 (a predecessor model of SyncroPatch 384PE)

This Webinar covers the general setup of the and features of this automated patch clamp device.

Patchliner

11.03.2021 | Webinar: automated patch clamp webinar high throughput functional evaluation of melanocortin and a CiPA based evaluation of proarrhythmic risk

icon sp96  SyncroPatch 384i 

Date: March 11. 2021

210311 SP384 March 11 Webinar CRL UMich V1

Speakers:

Ciria Hernandez, MD, Ph.D
(Assistant Research Scientist  - University of Michigan Life Sciences Institute)

Yuri Kuryshev
(Principal Scientist - Charles River Laboratories)



27.01.2021 | Webinar: Thinking outside the cardiac box

icon pl  Patchliner and Icon FLEX FLEXcyte 96 Webinar

Date: January 27. 2021

210127 webinar cardiac box

Speaker: 
Dr. Elena Dragicevic (Senior Sales and Alliance Manager; Nanion Technologies)

 

 

14.10.2020 | Webinar: Measurement of Transient receptor potential cation (TRP) channels using the Patchliner and Port-a-Patch

icon pap  Port-a-Patch and icon pl Patchliner Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. András Horváth (Nanion Technologies; Germany)


This is an on-demand webinar from Nan]i[on and Friends 2020.

14.10.2020 | Webinar: Development and validation of ASIC1a ligand-gated ion channel drug discovery assays on automated patch clamp platforms.

icon sp96  SyncroPatch 384i and icon pl Patchliner Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Marc Rogers (Metrion Biosciences; U.K.)


This is an on-demand webinar from Nan]i[on and Friends 2020.

14.10.2020 | Webinar: Pharmacological Characterization of Natural Tobacco Alkaloids in the Presence of Positive Allosteric Modulators Against Humana4b2 and a7 Nicotinic Acetylcholine Receptors

 icon pl Patchliner Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Omar Alijevic (Philip Morris International)


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: Evaluation of possible proarrhythmic potency: variability of IC50 values of drugs under different conditions and in different platforms

 icon pl Patchliner Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Péter Orvos (University of Szeged)


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: ICH S7B best practices considerations - New Q&As and Benchmarking best practices

 icon pl Patchliner and  icon sp96 SyncroPatch 384i Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Sonja Stoelzle-Feix (Nanion Technologies)

 


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: Benchmarking best practices and calibration standards for HTS hERG recordings for improved proarrhythmic assessment

 icon pl Patchliner and  icon sp96 SyncroPatch 384i Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Alison Obergrussberger (Nanion Technologies)

 


This is an on-demand webinar from Nan]i[on and Friends 2020.

16.10.2020 | Webinar: Voltage-Gated Ion Channels Fenestrations as a Drug Access Pathway

 icon pl Patchliner Webinar

Date: October 16. 2020

201012 Blog Image VUM 2020

Speakers:

Prof. Tamer M. Gamal El-Din (University of Washington)


This is an on-demand webinar from Nan]i[on and Friends 2020.

28.04.2020 | Webinar: Validation and optimization of automated patch clamp voltage-gated Ca2+ channel assays

icon pl   Patchliner Webinar

Date: April 28. 2020, 4:00 PM CET (10:00 AM EDT)

200605 blog image Patchliner Webinar Playback

Marc will outline the development, optimization and validation of a range of voltage-gated Ca2+ channel assays on the Patchliner automated patch clamp platform that were subsequently used in an 8 year drug discovery collaboration between Metrion Biosciences and a german pharma company.

Speakers:
Dr. Marc Rogers (Chief Scientific Officer, Metrion Biosciences)
Dr. András Horváth (Application Scientist, Nanion Technologies)

20.11.2018 | Webinar: The RELEVANCE of ion channel interplay – Voltage-activated channels in non-excitable cells

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i),   icon pl   Patchliner,   icon pap   Port-a-Patch Webinar

Date: November 20. 2018, 4:00 PM CET (11:00 AM EDT)

181120 event image Relevance project Webinar

The Webinar focuses on the automated patch clamp assay development for the study of red blood cells in health and disease and the RELEVANCE project, an international consortium of 13 partners from academia, diagnostic labs, blood supply centers, and small companies that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood cell function in health and disease. To this end, Nanion contributes assays for the electrophysiological characterization of healthy and patient-derived red blood cells.

12.09.2018 | Webinar: CiPA study: Bridging ion channel and myocyte data

180912 event image CiPAII Webinar

Icon CE   CardioExcyte 96,   icon pl   Patchliner and   icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i) Webinar

Date: September 12, 4:00 PM CEST (10:00 AM EDT)

 Get up-to-date with the CiPA progress of the Myocyte and Ion Channel Work Goups:

  • CiPA myocyte phase II validation study results: cross-site comparison using the CardioExcyte 96
  • HTS Phase I study: an update on progress of the CiPA Ion Channel Work Stream using the SyncroPatch 384PE and Patchliner

27.06.2017 | Webinar: New Dynamics in Automated Patch Clamp

icon pl   Patchliner

170612 blog image Pl WebinarThis webinar shows new applications on dynamic patch clamp of iPSC-derived cardiomyocytes and introduces an assay on KCa3.1 expressed in erythrocytes.

Speakers:

Dr. Teun P. de Boer, University Medical Center Utrecht
Title: Dynamic clamping on a Patchliner: adding virtual IK1 channels to cardiomyocytes

Maria Giustina Rotordam, Nanion Technologies
Title: Activation of hKCa3.1 by internal calcium exchange.

28.07.2015 | Webinar: High Throughput and High Fidelity: Automated Patch Clamp in Screening and Research

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i) and   icon pl   Patchliner 

The webinar covers the use of the Patchliner and the SyncroPatch 384/768PE for characterization of ion channels and screening of ion channel active compounds.

11.05.2013 | Webinar: Patchliner - unlimited experimental freedom

icon pl   Patchliner   Patchliner - unlimited experimental freedom

This Webinar covers the features of the Patchlliner, including the "minimized cell usage" for expensive cells.

Port-a-Patch

14.10.2020 | Webinar: Measurement of Transient receptor potential cation (TRP) channels using the Patchliner and Port-a-Patch

icon pap  Port-a-Patch and icon pl Patchliner Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. András Horváth (Nanion Technologies; Germany)


This is an on-demand webinar from Nan]i[on and Friends 2020.

14.10.2020 | Webinar: TRP channels in human corneal cells and their role in ophthalmology

icon pap  Port-a-Patch Webinar

Date: October 14. 2020

201012 Blog Image VUM 2020

Speakers:

Prof. Dr. Stefan Mergler (Charité - Universitätsmedizin Berlin; Germany)


This is an on-demand webinar from Nan]i[on and Friends 2020.

20.11.2018 | Webinar: The RELEVANCE of ion channel interplay – Voltage-activated channels in non-excitable cells

icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i),   icon pl   Patchliner,   icon pap   Port-a-Patch Webinar

Date: November 20. 2018, 4:00 PM CET (11:00 AM EDT)

181120 event image Relevance project Webinar

The Webinar focuses on the automated patch clamp assay development for the study of red blood cells in health and disease and the RELEVANCE project, an international consortium of 13 partners from academia, diagnostic labs, blood supply centers, and small companies that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood cell function in health and disease. To this end, Nanion contributes assays for the electrophysiological characterization of healthy and patient-derived red blood cells.

07.10.2015 | Webinar: Patch Clamp Made Easy, Fast Track to Excellence

icon pap   Port-a-Patch

This webinar shows applications that go way beyond possibilities of conventional patch-clamping, where the Port-a-Patch facilitates completely novel scientific directions.

CardioExcyte 96

13.10.2020 | Webinar: Impedance measurements and Calcium imaging to investigate the role of store operated Ca2+ entry in GPCR-mediated endothelial barrier regulation

Icon CE  CardioExcyte 96 Webinar

Date: October 13. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Judith Stolwijk (University Hospital Regensburg; Germany)


This is an on-demand webinar from Nan]i[on and Friends 2020.

13.10.2020 | Webinar: Profiling the pharmacology of G-Protein coupled receptors (GPCR) in cell-based assays using label-free impedance analysis

Icon CE  CardioExcyte 96 Webinar

Date: October 13. 2020

201012 Blog Image VUM 2020

Speakers:

Michael Skiba (University Hospital Regensburg; Germany)


This is an on-demand webinar from Nan]i[on and Friends 2020.

15.10.2020 | Webinar: Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity

 Icon CE CardioExcyte 96 Webinar

Date: October 15. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Tamer M. Mohamed (University of Louisville)


This is an on-demand webinar from Nan]i[on and Friends 2020.

17.03.2020 | Webinar: A new technology to evaluate mature cardiac contractility on high throughput level

Icon FLEX   FLEXcyte 96,   Icon CE   CardioExcyte 96 Webinar

Date: March 17. 2020, 4:00 PM CET (11:00 AM EDT)

200207 blog image Webinar Announcement FLEXcyte

The Webinar focuses on the FLEXcyte 96 technology, an Add-on of the CardioExcyte 96 instrument. The analysis of cardiomyocyte contractility as well as data of short-termed and long-termed compound applications is discussed.  

Speakers:
Dr. Sonja Stölzle-Feix
Dr. Matthias Gossmann

12.09.2018 | Webinar: CiPA study: Bridging ion channel and myocyte data

180912 event image CiPAII Webinar

Icon CE   CardioExcyte 96,   icon pl   Patchliner and   icon sp96   SyncroPatch 384PE (a predecessor model of SyncroPatch 384i) Webinar

Date: September 12, 4:00 PM CEST (10:00 AM EDT)

 Get up-to-date with the CiPA progress of the Myocyte and Ion Channel Work Goups:

  • CiPA myocyte phase II validation study results: cross-site comparison using the CardioExcyte 96
  • HTS Phase I study: an update on progress of the CiPA Ion Channel Work Stream using the SyncroPatch 384PE and Patchliner

28.04.2015 | Webinar: Excited About Contraction – Combining Contractility and Excitability Measurements in Cardiotoxicity Screening

Icon CE   CardioExcyte 96

This Webinar covers the introduction of the CardioExcyte 96, a hybrid device for impedance- and MEA-type recordings from intact, beating networks of stem cell-derived cardiomyocytes.

FLEXcyte 96

27.02.2021 | Presentation: Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment (In Japanese)

Icon FLEX FLEXcyte 96 Presentation

Date: February 27. 2021

210226 event image JSPS 2021

Speaker:
Mitsuyoshi Shimane (Nanion K.K Japan)

 

 

27.01.2021 | Webinar: Thinking outside the cardiac box

icon pl  Patchliner and Icon FLEX FLEXcyte 96 Webinar

Date: January 27. 2021

210127 webinar cardiac box

Speaker: 
Dr. Elena Dragicevic (Senior Sales and Alliance Manager; Nanion Technologies)

 

 

17.03.2020 | Webinar: A new technology to evaluate mature cardiac contractility on high throughput level

Icon FLEX   FLEXcyte 96,   Icon CE   CardioExcyte 96 Webinar

Date: March 17. 2020, 4:00 PM CET (11:00 AM EDT)

200207 blog image Webinar Announcement FLEXcyte

The Webinar focuses on the FLEXcyte 96 technology, an Add-on of the CardioExcyte 96 instrument. The analysis of cardiomyocyte contractility as well as data of short-termed and long-termed compound applications is discussed.  

Speakers:
Dr. Sonja Stölzle-Feix
Dr. Matthias Gossmann

Orbit Product Family

17.09.2020 | Webinar: Electrophysiological investigation of integral membrane proteins using the Orbit mini

Icon Orbit Mini  Orbit mini Webinar

Date: September 17. 2020, 4:00 PM CET (10:00 AM EDT)

200917 blog image orbit mini webinar

Speakers: 

Dr. Conrad Weichbrodt (Senior Scientist / Product Manager Orbit family; Nanion Technologies)

 

28.06.2018 | Webinar: Artificial Lipid Bilayers in focus: Hand-held DNA-sequencing and biosensing with nanopores

180628 event image webinar Orbit Icon Orbit Mini   Orbit mini and   Icon Orbit   Orbit 16

Learn about single channel measurements in bilayer recording using the orbit instrument family

- Simplifying artificial bilayer experiments: Single-molecule experiments on micro-cavity arrays
- Hand-held DNA-sequencing and biosensing with nanopores 

27.01.2016 | Webinar: Instant bilayers - just add protein.

Icon Orbit   Orbit 16 and   Icon Orbit Mini   Orbit Mini

Orbits V1 flat 250pxThis webinar covers the use of the lipid bilayer platforms from Nanion: the Orbit16 and the Orbit mini for characterization of membrane proteins like ion channels, bacterial porins and biological nanopores. Both bilayer systems support high quality low noise recordings, but differ in throughput capabilities and experimental features. The Orbit16, introduced in 2012 is a device for efficient formation of 16 lipid bilayers simultaneously, allowing for parallel bilayer-reconstitution of ion channels and nanopores.

 

SURFE²R Product Family

06.05.2021 | Webinar: Secondary transport inhibition and regulation by SSM-electrophysiology

Icon N1  SURFE2R N1

Date: May 5th. 2021

210507 OnDemand Surfer

Speakers:

Professor Dr. Christine Ziegler
(University of Regensburg, Faculty of Biology and Pre-Clinics, Institute of Biophysics and physical Biochemistry, Structural Biology-Biophysics II)

Professor Dr. Camilo Perez
(University of Basel, Biozentrum, Center for Molecular Life Sciences)

18.03.2021 | Webinar: Understanding Drug Efflux – Small Multidrug Resistance Family - Stoichiometry and Specificity

Icon N1  SURFE2R N1

Date: March 18. 2021

210318 Session1 SURFE2R N1 Now On Demand

Speakers:

Randy Stockbridge
(Assistant Professor, Department of Molecular, Cellular, and Developmental Biology - University of Michigan)


Katherine Henzler-Wildman
(Professor Biochemistry, Department of Biochemistry - University of Wisconsin-Madison)

13.10.2020 | Webinar: Employing SSM electrophysiology to capture electrogenic fluxes in membrane proteins

Icon N1  SURFE2R N1 Webinar

Date: October 13. 2020

201012 Blog Image VUM 2020

Speakers:

Dr. Matthias Quick (Columbia University; NY, USA)


This is an on-demand webinar from Nan]i[on and Friends 2020.

16.06.2020 | Webinar: Functional studies on membrane transporters using the SURFE²R N1

Icon N1  SURFE²R N1 Webinar

Date: June 16. 2020, 4:00 PM CET (10:00 AM EDT)

200618 blog image Webinar Playback SURFE2R N1

Speakers: 

Dr. Maria Barthmes (Product Manager, Nanion Technologies)
Dr. Andre Bazzone  (Application Scientist, Nanion Technologies)

19.05.2020 | Webinar: Insights and New Approaches in Transporter Characterization - SURFE²R N1

Icon N1  SURFE²R N1 Webinar

Date: May 19. 2020, 4:00 PM CET (10:00 AM EDT)

202705 blog image SURFE2R Webinar OnDemand

Speakers: 

Dr. Maria Barthmes (Product Manager, Nanion Technologies)
Nathan Thomas (5th Year PhD, University of Wisconsin-Madison [Dr. Henzler-Wildman's lab])
Prof. Dr. Camilo Perez (Head of Research Group - BIOZENTRUM, University of Basel, Switzerland)

30.01.2018 | Webinar: The SURFE²R Technology: Assays for Parmacological and Functional Characterization of Membrane Transporters

Icon 96SE   SURFE²R 96SE and   Icon N1   SURFE²R N1

This webinar gives you an overview on the SURFE²R technology and its applications. Furthermore, we invited Dr. Thomas Licher (Sanofi Germany) as speaker, to present his work and experiences on the SURFE²R 96SE device.

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