Nanion Webinars


September 2021 - Automated patch clamp assay development for the study of red blood cells (RBCs) in health and disease

210907 EVIDENCE webinar LinkedIn 1200x627 Single Ad Image All

Presenters: 

Nicoletta Murciano
(PhD Candidate - Nanion Technologies )

Title: 
Automated patch clamp assay development for the study of red blood cells (RBCs) in health and disease

Dr. Lars Kaestner
(Professor - Saarland University)

Title: 
Introduction to EVIDENCE prognostic, diagnostic, and therapeutic approaches on RBC function in health and disease

Abstract: 

Calcium (Ca2+) is a universal signaling molecule and is critically important in regulating many physiological functions and survival of RBCs. Amongst others, intracellular Ca2+ controls cell volume and deformability. This process plays a substantial role in RBCs since their volume needs to adapt when passing blood vessel constrictions during the flow. Excessive Ca2+ uptake also leads to accelerated cell clearance causing anaemia.

Therefore, studying Ca2+ regulation is crucial to understand RBC diseases. Piezo1, KCa3.1 (Gardos channel) and NMDA receptors are three channels present in the RBC membrane and critical for Ca2+ regulation.

We developed functional assays to measure these channels in healthy and diseased RBCs populations using electrophysiological tools, contributing to the characterization of RBC diseases.

Date: 07. September 2021
Time: 4PM CEST, 10AM EDT

Register Here


Register for our monthly Newsletter and we will keep you informed.

Monthly Newsletter

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.