December 2021 - Structure and Function of Na+ and H+ dependent transporters
Dr. David Drew, Professor in Biochemistry (Stockholm University)
Title: Structure and mechanism of the Na+/H+ exchanger NHA2
Dr. Matthias Quick, Associate Professor of Neurobiology (Columbia University)
Title: The molecular mechanism of the Na+/H+ antiporter NhaA – from binding to flux
Na/H exchangers are a important and diverse family of secondary active transporters. These proteins are crucial in pH, sodium and volume homeostasis, dysfunction is critical in eukaryotes and procaryotes alike. In the final session of the Transporter Webinar Series David Drew and Matthias Quick share some of their research on the structure and function of this transporter family.