Nanion Webinars

September 2022 - Functional characterization and substrate binding kinetics of the Na+ cotransporters SGLT1 and GAT1

220908 Andre Rocco Webinar


Dr. Andre Bazzone, Senior Scientist (Nanion Technologies)
Title: Sugar binding and translocation in SGLT1: SSM-based electrophysiology reveals sugar occluded intermediates

Rocco Zerlotti, Ph.D. Student (Nanion Technologies)
Title: Individual charge translocations upon GABA, Na+ and Cl- binding to human GAT-1 indicate conformational flexibility

Session Abstract: 

In eucaryotes, sodium gradients are a common energy source to drive the uptake of a large variety of substrates. In the second session of our Transporter Webinar Series 2022, Andre Bazzone and Rocco Zerlotti will present new insights to Na+ dependent substrate translocation pathways. Studies on the sugar transporter SGLT1 and the neurotransmitter transporter GAT1 revealed detailed kinetic information from substrate induced, electrogenic pre steady-state reactions.

Date: 08. September 2022 (Join Live or Access On-Demand)
Time: 10 AM EDT, 4 PM CEST

Register Here

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.