• Nanion's Buffer Solutions

    Safe, accurate and ready-to-use

Buffer Solutions - Designed to set new standards

Reliable buffer solutions are critical for patch clamp applications. Our goal is to provide high-class recording solutions that leave you in no doubt about quality and stability.

Sophisticated quality management (QM) including the highest requirements for the purity of chemicals, regular tests on our patch clamp systems and long-term testing makes us your partner for demanding research projects and drug development. Our QM follows a completely transparent concept, which ends with meaningful certificates for quality and MSDS.

We are a team of electrophysiologists with over 18 years' experience in the design and production of buffer solutions for patch clamp experiments. We have used our knowledge and experience to put together a diverse portfolio of external and internal solutions so that you can get the most out of your experiments.

Buffer Solution Accordion Product Value Prop


Order Solutions

Our portfolio contains a wide variety of patch clamp solutions. Choose your solution, fill in the amount needed and simply send us your request:

Buffer Solution Accordion Product Sheet

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Testimonials and Customer List

At the Salk Institute I was actually using Nanion´s Buffer Solutions for my "traditional" old-school patch experiments. Nanion´s formulation was much more reliable and actually easier to patch with. It was more consistent, than what I could produce in-house!

Yusuf Tufail, Senior Scientist from the Salk Institute for Biological Studies in San Diego, California.

We are your partner for electrophysiology recording solutions for customized research and development. Nanion´s innovative, stable, long-life and ready-to-use buffer solutions are created for efficiency to facilitate your research and assist you in meeting tight deadlines.

Axel Brüggemann, Lab Manager, Nanion Technologies GmbH, Munich, Germany

Innovations in electrophysiology have created a strong demand for high quality buffer solutions capable of supporting smooth workflows for increasingly complex measurements with automated patch clamp systems. Certified, tested buffer solutions, using chemicals of the highest purity on the market have always been of paramount importance. Nanion brings together excellent buffer solution quality with minimal effort on your part to support electrophysiologists and their experiments.

Dr. Andrea Brüggemann, CSO and Owner of Nanion Technologies GmbH, Munich, Germany

We lost 2 months of work due to bad solutions caused by contaminated MilliQ water, now we are glad to use QC’ed Nanion solutions as soon as we have doubts about the quality of our water.

Dr. Michel De Waard, Group Leader, l'institut du thorax, Nantes, France

Product Sheet

Buffers and Solutions for the SyncroPatch 384i / 768i, Patchliner, Port-a-Patch

Reliable buffer solutions are critical for any electrophysiological application. Our goal, therefore, is to provide high-class recording solutions that leave you in no doubt about quality and stability. Our quality assurance includes chemical tests as well as tests on our patch clamp systems of each lot. Our buffers are shipped with the corresponding "Certificates of Analysis" and "Material Safety Data Sheets" (MSDS).

Available buffers and solutions
  • "External Standard", 500 mL: (Order # 08 3001)
  • "External Standard Ca 10", 500 mL: (Order # 08 3012)
  • "External NMDG 60", 500 mL: (Order # 08 3004)
  • "External NMDG 60 Ca 10", 500 mL: (Order # 08 3011)
  • "External [-] Ca2+ [-] Mg2+", 500 mL: (Order # 08 3003)
  • "Internal CsF 110", 500 mL: (Order # 08 3008)
  • "Internal KF 110", 500 mL: (Order # 08 3007)
  • "Washing solution", 5 L: (Order # 08 3010)

Buffer Solutions - Product Sheet

icon sp96   SyncroPatch 384, SyncroPatch 384i, SyncroPatch 384PE   icon pl   Patchliner and   icon pap   Port-a-Patch - Quality-assured buffer solution product sheet:  logo pdf   (2.8 MB)

SDS (Safety Data Sheet)


2021 - Ultrasound mediated cellular deflection results in cellular depolarization

Icon Buffer SolutionsBuffer Solution Publication in bioRxiv (2021)

Vasan A., Orosco J., Magara U., Duque M., Weiss C., Tufail Y., Chalasani S.H., Friend J.

2021 - Active components of Bupleurum chinense and Angelica biserrata showed analgesic effects in formalin induced pain by acting on Nav1.7

 icon pap  Port-a-Patch and   Icon Buffer Solutions  Buffer Solution Publication in Journal of Ethnopharmacology (2021)

Xu Y., Yu Y., Wang Q., Li W., Zhang S., Liao X., Liu Y., Su Y., Zhao M., Zhang J.

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