• CE Slide 1
  • CE Slide 2
  • CE slide 3
  • CE slide 4
  • CardioExcyte 96

    Combined impedance and MEA-like recordings
  • CardioExcyte 96

    For cardiac safety screening
  • CardioExcyte 96

    Next generation label-free cell analysis
  • CardioExcyte 96

    Intuitive data analysis & arrhythmia detection

Hepatocytes - Paracetamol toxicity on hepatocyte-like MetaHeps cells

Icon CE   CardioExcyte ParacetamolCardioExcyte data and applications:
Cells were kindly provided by MetaHeps.

The impedance signal recorded on the CardioExcyte 96 changes as a result of alterations in confluency, cell contact (morphological shape) and conductivity of adherent cells and thereby provides a measure of toxicity. MH cells from MetaHeps® were grown on NSP-96 plates and base impedance was monitored over time. Increasing concentrations of paracetamol induce a decrease in base impedance of MH cells which can be monitored continuously. Tween (2%) induced 100% cell death and was used as a positive control.

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