2019 - FLEXcyte: A New In Vitro Tool to Study Cardiac Contractility under Physiological Mechanical Conditions
FLEXcyte 96 poster, Nanion User Meeting USA 2019 (38.6 MB)
Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. Integration into standard lab procedures remains a challenge for current in vitro systems. The FLEXcyte 96 system has the potential to scale-up mechanical testing towards medium-throughput analyses. We show here that, using stem cell-derived cardiomyocytes, this system enables predictive recordings of contractile behavior in the presence of well-known reference compounds.