• FLEXcyte 96

    Measure true cardiac contractility
  • FLEXcyte 96

    Cardiomyocytes cultivated on a flexible membrane
  • FLEXcyte 96

    The complete setup fits on a lab benchtop
  • FLEXcyte 96

    Judge compound responses at a glance

2019 - FLEXcyte: A New In Vitro Tool to Study Cardiac Contractility under Physiological Mechanical Conditions

 Icon FLEX   FLEXcyte 96 poster, Nanion User Meeting USA 2019  logo pdf   (38.6 MB)

Abstract:

Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. Integration into standard lab procedures remains a challenge for current in vitro systems. The FLEXcyte 96 system has the potential to scale-up mechanical testing towards medium-throughput analyses. We show here that, using stem cell-derived cardiomyocytes, this system enables predictive recordings of contractile behavior in the presence of well-known reference compounds.

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