• FLEXcyte 96

    Cardiomyocytes cultivated on a flexible membrane
  • FLEXcyte 96

    Measure true cardiac contractility
  • FLEXcyte 96

    The complete setup fits on a lab benchtop
  • FLEXcyte 96

    Judge compound responses at a glance

Kinase inhibitors – Chronic compound effects on cardiomyocytes

FLEXcyte kinase inhibitor Chronic effect

Icon FLEX   FLEXcyte 96 data and applications:
Cells were kindly provided by Cellular Dynamics.

Here Structural and/or functional toxicity of Kinase inhibitors Trametinib, Sorafenib, Nilotinib and A-674563 was investigated. Compound incubation time was 5 days.

During investigations of chronic effects it could take days and weeks until onset of adverse effects. The CardioExcyte and FLEXcyte technology and the consumables are perfectly suited for such studies.

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FLEXcyte 96 Brochure

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