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    Most versatile automated patch clamp system on the market
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    More than 10 years experience in assay design and support
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    Automated Dynamic Clamp
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    All features & benefits of manual patch clamp

NaV1.5 - Lidocaine Block

application hnav15 3 small

icon pl   Patchliner data and applications:
Cells were kindly provided by Cytomyx/Millipore.

Full dose response curves at different holding potentials were recorded for each cell (hNav1.5 in HEK293). Currents were elicited by a 10 ms voltage step to 0 mV. Plotted are average peak currents as a function of holding potential and lidocaine concentration. 

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