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    Most versatile automated patch clamp system on the market
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    More than 10 years experience in assay design and support
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    All features & benefits of manual patch clamp

Acetylcholine Receptor Alpha 7 - "Human a7 nicotinic Acetylcholine Receptor on the Patchliner "

icon pl   Patchliner application note:   logo pdf   (0.2 MB)
Cells were kindly provided by Galantos.


The human a7 nicotinic acetylcholine receptor expressing cells (stable) from Galantos Pharma GmbH were tested on the Patchliner. Repeated stimulations with 100 μM nicotine were tested to validate the system. In a run, six out of eight cells could be measured. All six cells showed characteristic a7 currents. Average peak currents for the shown experiment were 0.9 ± 0.2 nA (n = 6) which is consistent with manual patch clamp results reported by Galantos Pharma.

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