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  • Patchliner

    Most versatile automated patch clamp system on the market

  • Patchliner

    In-house production and QC of consumables

  • Patchliner

    More than 10 years experience in assay design and support

  • Dynamite8

    Automated Dynamic Clamp

  • Patchliner

    All features & benefits of manual patch clamp

KCa1.1 (BK) - Activation by Internal Calcium

BK verticalicon pl   Patchliner data and applications: 

Top: BK (KCa1.1) current voltage relationships in a single cell showing effects of changing the intracellular free Ca2+ concentration (15 nM, n = 9; 108 nM, n = 11; 316 nM, n = 11).

Bottom: Comparison of BK (KCa1.1) current voltage relationships obtained on a conventional patch clamp setup (closed circles, n = 10) and on the Patchliner (open circles, n = 11).
Data are taken from Milligan C.J. et al., Nature Protocols, 2009, 4(2), 244-255.

   

 

 

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