• Patchliner

    Most versatile automated patch clamp system on the market
  • Patchliner

    In-house production and QC of consumables
  • Patchliner

    More than 10 years experience in assay design and support
  • Dynamite8

    Automated Dynamic Clamp
  • Patchliner

    All features & benefits of manual patch clamp

Piezo 1: Mechanical stimulation and therapeutic potential

icon pl   Patchliner application note:   logo pdf   (0.5 MB)

PIEZO channels are mechanically activated cation channels, mediating various health and disease mechanisms.

Summary:

PIEZO channels are mechanically activated cation channels, mediating various health and disease mechanisms such as red blood cell homeostasis, malarial resistance, vascular structure and function, and lymphoedema. Nanion’s Patchliner enables mechanical stimulation of PIEZO1 channels in an automated patch clamp instrument, allowing for reliable quantification of PIEZO1 activation by fluid flow and Yoda1.

Find the Target Note here

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