• Port-a-Patch mini

    A small revolution: The amplifier is integrated
  • Port-a-Patch mini

    Fits on every desk and is simply connected to a computer via a USB cable
  • Port-a-Patch mini

    Smallest patch clamp setup in the world

NaV1.5 - Tetracaine concentration response curve

PaP mini NaV15 Tetracaine DRC TC Traces

icon papm   Port-a-Patch mini data and applications:
Cells were kindly provided by Charles River.

The image shows the timecourse of the experiment (top) where peak amplitude is plotted against time and example traces in control conditions and different concentrations of tetracaine are also shown in the insert. The concentration reponse curve for tetracaine is shown on the bottom for an average of 6 cells. The curve is fit with a Hill equation revealing an IC50 = 25.5 ±  5.7 µM (n = 6). 

 

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