NaV1.5 - Tetracaine concentration response curve
Port-a-Patch mini data and applications:
Cells were kindly provided by Charles River.
The image shows the timecourse of the experiment (top) where peak amplitude is plotted against time and example traces in control conditions and different concentrations of tetracaine are also shown in the insert. The concentration reponse curve for tetracaine is shown on the bottom for an average of 6 cells. The curve is fit with a Hill equation revealing an IC50 = 25.5 ± 5.7 µM (n = 6).