• Port-a-Patch

    Smallest patch clamp setup in the world
  • Port-a-Patch

    Easy to learn - ideal for teaching
  • Port-a-Patch

    Records from cells, organelles and bilayers
  • Port-a-Patch

    First planar patch clamp device on the market
  • Port-a-Patch

    Ideal for internal solution exchange applications

KV1 (Shaker-related Potassium Channels) - Mutation without Inactivation

application shaker 1icon pap   Port-a-Patch data and applications: 
Data were kindly provided by Dr. Kenton Swartz, NIH, Bethesda, USA.

Here we show recordings from HEK293 cells transiently expressing a Shaker K mutant that has its inactivation removed (Shaker-IR). The holding potential was -80 mV. The current-voltage relationship of the tail currents reveals a half-activating potential of -27 mV.

 

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