• Port-a-Patch

    Smallest patch clamp setup in the world
  • Port-a-Patch

    Easy to learn - ideal for teaching
  • Port-a-Patch

    Records from cells, organelles and bilayers
  • Port-a-Patch

    First planar patch clamp device on the market
  • Port-a-Patch

    Ideal for internal solution exchange applications

2011 - Cardiac Toxicity

icon pl   Patchliner and   icon pap   Port-a-Patch book chapter in ADMET for Medicinal Chemists: A Practical Guide (2011)

Authors: 
Kettenhofen R., Schwengberg S.

 

Book chapter:
ADMET for Medicinal Chemists: A Practical Guide, Edited by Katya Tsaioun and Steven A. Kates, John Wiley & Sons, Inc. (2011) 287 - 314


Keywords: 

  • cardiac toxicity and nonarrhythmic cardiac toxicity;
  • preclinical models for assessment - of ion channel-related cardiotoxicity;
  • pluripotent stem cell-derived cardiomyocytes - either from mouse or human origin, promising cellular models combining cell line advantages

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