KV1 (Shaker-related Potassium Channels) - Mutation without Inactivation

  Port-a-Patch data and applications: 
Data were kindly provided by Dr. Kenton Swartz, NIH, Bethesda, USA.

Here we show recordings from HEK293 cells transiently expressing a Shaker K mutant that has its inactivation removed (Shaker-IR). The holding potential was -80 mV. The current-voltage relationship of the tail currents reveals a half-activating potential of -27 mV.

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