Kir Channels - Response to Different External Potassium Concentrations
Current response in RBL cells to a voltage ramp from –150 mV to +80 mV in the presence of a low and a high external K+ concentration (left). Voltage dependent block of the inward K+ current after the external additon of 50 µM Ba2+ (middle). Same block in response to a continuous voltage step to –150 mV (right) from 0 mV. Low K+ (4.5 mM K+), high K+ (143 mM K+).